Association between restless legs syndrome and depression in patients with chronic kidney disease
作者： Maria Eszter Czira , Gyorgy Deak , Anett Virag Lindner , Lilla Szeifert , Peter Torzsa
DOI: 10.1016/J.JPSYCHORES.2009.05.004
关键词:
摘要: Restless legs syndrome (RLS) is reportedly associated with depression. This association may be mediated by both sleep-dependent and sleep-independent mechanisms. Here we analyze the between RLS depressive symptoms in patients chronic kidney disease (CKD). We also assessed whether relationship independent of insomnia. In a cross-sectional study, socio-demographic parameters, laboratory data, medical history were collected from 788 transplant 161 dialyzed patients. Insomnia, depression, presence standard questionnaires. Patients probable had higher prevalence than those without (56% vs. 22% RLS, respectively; P<.001). presenting Athens Insomnia Scale (AIS) scores [median AIS score (interquartile range): 7 (6) 3 (4) P<.001]. The correlated CES-D (Spearman's rho=0.54, multivariate analysis, was independently (OR=3.96, 95% CI 2.21-7.1, remained significant even after including insomnia model (OR=2.9, 1.55-5.43, depression CKD. accounting for Sleep-independent mechanisms contribute to
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