Characterization of glycolytic metabolism and ion transport of Candida albicans.
作者： Martha Calahorra , Norma Silvia Sánchez , Antonio Peña
DOI: 10.1002/YEA.2915
关键词:
摘要: The main energetic pathways, fermentation and respiration, the general ion transport properties of Candida albicans were studied. Compared to Saccharomyces cerevisiae, we found that in C. albicans: (a) cell mass yield when grown YPD was significantly larger; (b) it required longer times be starved endogenous substrates; (c) ethanol production lower but significant; (d) respiration also lower; (e) showed a small activity an alternative oxidase; (f) oxidative phosphorylation seemed compete for both ADP NADH; (g) NADH levels lower. Regarding compared S. cerevisiae: mechanism similar, with plasma membrane H+-ATPase generates ΔpH ΔΨ, latter being responsible driving K+ inside; its acidification capacity is slightly smaller less sensitive activation by high pH; presence results large fermentation, most probably due energy process. produced stimulation pH or addition at low increase fermentation. Copyright © 2012 John Wiley & Sons, Ltd.
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