Examination of the least-squares method applied to the evaluation of physicochemical parameters with linearized equations

摘要: Physicochemical parameters are frequently evaluated by the least-squares method after linearization of equation which relates experimental variables to interest. When a given set data is treated evaluate (n+1) parameters. (n+2) nominally identical linearized equations possible; each these leads different sets values also affected variances. These differences observed when statistical weights used. Two methods for establishing one best fitting data, i.e., simulation experiments and propagation errors, discussed, compared applied potentiometric determination two stepwise metal/ligand equilibrium constants approximately equal value.