Swept-source and optical coherence tomography angiography in patients with X-linked retinoschisis.

摘要: To explore the structural features of juvenile X-linked retinoschisis (XLRS) using swept-source-optical coherence tomography (SS-OCT) and optical angiography (OCT-A). Retrospective, observational cross-sectional study. Nine patients (18 eyes) diagnosed with XLRS were included. SS-OCT OCT-A used to evaluate characteristics inner/outer retina choroid. showed that inner nuclear layer (INL) was most commonly affected area (16/18 eyes; 89%). No significant differences in central macular thickness (CMT) or subfield choroidal (SFCT) evidenced between eyes (CMT: 364 μm right eye vs 320 μm left eye; SFCT: 305 307 μm; P=0.895). Best-corrected visual acuity (BCVA) did not correlate CMT (rs= −0.19; P=0.445) SFCT (rs=0.06; P=0.795). BCVA significantly correlated following defects: outer plexiform (OPL; rs=0.50; P=0.036); external limiting membrane (ELM; rs=0.65; P=0.003); ellipsoid portion segment (EPIS; rs=0.67; P=0.002); cone tips (COST; rs=0.69; P=0.001). Schisis at INL revealed a spoke-like pattern foveal region reticular parafoveal on en-face imaging. In cases which schisis OPL, multiple polygonal hyporeflective cavities observed region. The spaces primarily located OPL. SFCT; however, ELM, EPIS, COST defects worse BCVA. There positive correlation age SFCT.