Differential Diagnosis of Pediatric Multiple Sclerosis.

摘要: The differential diagnosis of pediatric multiple sclerosis (MS) can be broad and pose diagnostic challenges, particularly at initial presentation. Among demyelinating entities, neuromyelitis optica spectrum disorders (NMOSD), myelin oligodendrocyte glycoprotein antibodies (MOG-ab) associated disorders, acute disseminated encephalomyelitis (ADEM) are now well-known as unique disease processes yet continue to overlap with MS in regards clinical presentation imaging. In non-inflammatory such metabolic leukodystrophies, an erroneous made even while applying appropriate criteria. Knowing the epidemiology, typical presentation, criteria, ancillary test results each disease, aid making correct by contrasting these features those MS. Determining early, allows for efficient effective treatment well prognostication.