Clinical and laboratory features in the early stage of severe acute respiratory syndrome.

作者: Feng Yee Chang , Ning Chi Wang , Jung Chung Lin , Kuo Ming Yieh , Cheng Kuo Fan

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摘要: Background and purpose To characterize the clinical laboratory features of severe acute respiratory syndrome (SARS) in early stage to compare them with those patients initially suspected having SARS who were later determined have other febrile diseases. Methods Between March June 2003, 122 possible admitted isolation ward Tri-Service General Hospital. was diagnosed according modified World Health Organization case definition (May 1, 2003). Among them, 43 classified as probable cases a etiology excluded 32 patients. Results Presenting symptoms on admission included fever (97.7% cases, 84.4% cases), chills (39.5% vs 18.8%), cough sputum production (16.3% 40.6%), dry (23.3% 9.4%), dyspnea (18.6% diarrhea (14.0% none), rhinorrhea (2.3% myalgia (7.0% 6.6%). Common lymphopenia elevated aspartate aminotransferase, alanine lactate dehydrogenase, C-reactive protein creatine kinase values. Intubation mechanical ventilation required 12 6 cases. Five (11.6%) died. A scoring system which developed differentiate from emergency room could sensitivity 36.4% specificity 70.6%. Conclusions The presentation at do not allow differentiation SARS-CoV infection Thus, it is mandatory for all healthcare workers strictly follow standard precautions during an outbreak minimize disease transmission.

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