Next generation, high relaxivity gadolinium MRI agents.
作者： Kenneth N. Raymond , Valérie C. Pierre
DOI: 10.1021/BC049817Y
关键词:
摘要: Department of Chemistry, University California, Berkeley, California 94720-1460 . Received July 27, 2004Magnetic resonance imaging (MRI) has evolved intoone the most powerful techniques in diagnostic clinicalmedicine and biomedical research by enabling ac-quisition high resolution, three-dimensional images ofthe distribution water vivo (
acs.org
berkeley.edu 参考文章(35)
Ernö Brücher, Kinetic Stabilities of Gadolinium(III) Chelates Used as MRI Contrast Agents Topics in Current Chemistry. ,vol. 221, pp. 103- 122 ,(2002) , 10.1007/3-540-45733-X_4
H. Gries, Extracellular MRI Contrast Agents Based on Gadolinium Topics in Current Chemistry. ,vol. 221, pp. 1- 24 ,(2002) , 10.1007/3-540-45733-X_1
Luca Frullano, Jan Rohovec, Joop A. Peters, Carlos F. G. C. Geraldes, Structures of MRI Contrast Agents in Solution Topics in Current Chemistry. ,vol. 221, pp. 25- 60 ,(2002) , 10.1007/3-540-45733-X_2
Éva Tóth, Lothar Helm, André E. Merbach, Relaxivity of MRI Contrast Agents Topics in Current Chemistry. ,vol. 221, pp. 61- 101 ,(2002) , 10.1007/3-540-45733-X_3
Andre E. Merbach, Eva Toth, Water exchange dynamics: the key for high relaxivity contrast agents in medical magnetic resonance imaging Ach-models in Chemistry. ,vol. 135, pp. 873- 884 ,(1998)
Tsan-Hwang Cheng, Yun-Ming Wang, Kuei-Tang Lin, Gin-Chung Liu, Synthesis of four derivatives of 3,6,10-tri(carboxymethyl)-3,6,10-triazadodecanedioic acid, the stabilities of their complexes with Ca(II), Cu(II), Zn(II) and lanthanide(III) and water-exchange investigations of Gd(III) chelates Journal of The Chemical Society-dalton Transactions. pp. 3357- 3366 ,(2001) , 10.1039/B107456N
Adam R. Johnson, Brendon O'Sulliva, Kenneth N. Raymond, Synthesis of a ligand based upon a new entry into the 3-hydroxy-N-alkyl-2(1H)-pyridinone ring system and thermodynamic evaluation of its gadolinium complex. Inorganic Chemistry. ,vol. 39, pp. 2652- 2660 ,(2000) , 10.1021/IC991471T
Seth M. Cohen, Jide Xu, Emil Radkov, Kenneth N. Raymond, Mauro Botta, Alessandro Barge, Silvio Aime, Syntheses and relaxation properties of mixed gadolinium hydroxypyridinonate MRI contrast agents. Inorganic Chemistry. ,vol. 39, pp. 5747- 5756 ,(2000) , 10.1021/IC000563B
Silvio Aime, Mauro Botta, Mauro Fasano, Simonetta Geninatti Crich, Enzo Terreno, 1H and 17O-NMR relaxometric investigations of paramagnetic contrast agents for MRI. Clues for higher relaxivities Coordination Chemistry Reviews. ,vol. 185, pp. 321- 333 ,(1999) , 10.1016/S0010-8545(98)00277-X
L. Thunus, R. Lejeune, Overview of transition metal and lanthanide complexes as diagnostic tools Coordination Chemistry Reviews. ,vol. 184, pp. 125- 155 ,(1999) , 10.1016/S0010-8545(98)00206-9