摘要: Publisher Summary The relationship between age and the morbidity mortality of systemic lupus erythematosus (SLE) is important incidence disease varies in males females depending on age. Gender more specifically sex steroids play an role maturation organ systems that affect animals throughout life are therefore to health most vertebrates. effects immune system profound long-lasting because they control growth various cell may also influence susceptibility through modulation populations, alteration cytokine levels, populations processes such as apoptosis, change very basic molecular mechanisms. Lupus one highly affected by hormones. Thus, potent modulators immunity all animal systems. They patients with SLE help explain fluctuant activity disease. Their their effect development organs brain could some abnormalities found these