Cytokeratins of the Stratum Medium and Stratum Internum of the Equine Hoof Wall in Acute Laminitis
作者： O Wattle
DOI: 10.1186/BF03549627
关键词:
摘要: The cytoskeleton of living keratinocytes consists mainly cytokeratins that have polymerised into intermediate filaments. aim this study was to describe the expression in epidermal cells weight-bearing parts equine hoof wall during acute spontaneous laminitis. A total 9 hooves from 3 horses subjected euthanasia within 48 h first clinical signs laminitis were sectioned and examined. stratum medium internum characterized by 1- 2-dimensional gel electrophoresis, tissue distribution studied immunohistochemical staining. biochemical results showed same set as seen 8 normal horses, reported on previously, used controls. indicated a difference between with content basal matrix suprabasal at mid level wall. However, no conclusion could be drawn whether change cytokeratin primary or caused initiation local tissue-repairing process.
biomedcentral.com
springer.com 
sci-hub.st 参考文章(20)
E. J. Finocchio, J. H. Johnson, M. M. Guffy, J. R. Coffman, Hoff circulation in equine laminitis. Javma-journal of The American Veterinary Medical Association. ,vol. 156, pp. 76- 83 ,(1970)
B. C. Powell, G. E. Rogers, The role of keratin proteins and their genes in the growth, structure and properties of hair Jolles, P [Editor], Zahn, H [Editor], Hoecker, H [Editor] Experientia Supplementum (Basel); Formation and structure of human hair. ,vol. 78, pp. 59- 148 ,(1997) , 10.1007/978-3-0348-9223-0_3
M. Tainsky, E. Fuchs, C. Byrne, Programming gene expression in developing epidermis Development. ,vol. 120, pp. 2369- 2383 ,(1994) , 10.1242/DEV.120.9.2369
O. WATTLE, Cytokeratins of the equine hoof wall, chestnut and skin: bio‐ and immunohisto‐chemistry Equine Veterinary Journal. ,vol. 30, pp. 66- 80 ,(2010) , 10.1111/J.2042-3306.1998.TB05124.X
Elaine Fuchs, Don W Cleveland, A Structural Scaffolding of Intermediate Filaments in Health and Disease Science. ,vol. 279, pp. 514- 519 ,(1998) , 10.1126/SCIENCE.279.5350.514
P. Martin, Wound Healing--Aiming for Perfect Skin Regeneration Science. ,vol. 276, pp. 75- 81 ,(1997) , 10.1126/SCIENCE.276.5309.75
E Fuchs, Keith R. Porter Lecture, 1996. Of mice and men: genetic disorders of the cytoskeleton. Molecular Biology of the Cell. ,vol. 8, pp. 189- 203 ,(1997) , 10.1091/MBC.8.2.189
C. C. POLLITT, M. DARADKA, Equine laminitis basement membrane pathology: loss of type IV collagen, type VII collagen and laminin immunostaining. Equine Veterinary Journal. ,vol. 30, pp. 139- 144 ,(2010) , 10.1111/J.2042-3306.1998.TB05133.X
H M Hazelbag, L J van den Broek, E B van Dorst, G J Offerhaus, G J Fleuren, P C Hogendoorn, Immunostaining of chain-specific keratins on formalin-fixed, paraffin-embedded tissues: a comparison of various antigen retrieval systems using microwave heating and proteolytic pre-treatments. Journal of Histochemistry and Cytochemistry. ,vol. 43, pp. 429- 437 ,(1995) , 10.1177/43.4.7534785
Giorgio Cattoretti, Stefano Pileri, Carlo Parravicini, Michael H. G. Becker, Simonetta Poggi, Carlo Bifulco, Göran Key, Lucia D'Amato, Elena Sabattini, Elisa Feudale, Fred Reynolds, Johannes Gerdes, Franco Rilke, Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections The Journal of Pathology. ,vol. 171, pp. 83- 98 ,(1993) , 10.1002/PATH.1711710205