Phosphorylcholine-based polymers and their use in the prevention of biofouling

作者: Andrew L. Lewis

DOI: 10.1016/S0927-7765(99)00152-6

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摘要: This article provides an overview of work carried out on the synthesis and non-fouling properties phosphorylcholine (PC)-containing polymers. The concept biomimicry is outlined major classes synthetic PC-based materials described. Studies interaction these with various proteins are collated mechanism for their protein-resistant nature discussed. Similarly, cellular interactions also reviewed, ex-vivo in-vivo clinical data provided to demonstrate usefulness improving medical devices.

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