Patient-Reported Outcomes After Radiation Therapy in Men With Prostate Cancer: A Systematic Review of Prognostic Tool Accuracy and Validity.

摘要: Purpose To identify, through a systematic review, all validated tools used for the prediction of patient-reported outcome measures (PROMs) in patients being treated with radiation therapy prostate cancer, and provide comparative summary accuracy generalizability. Methods Materials PubMed EMBASE were searched from July 2007. Title/abstract screening, full text critical appraisal undertaken by 2 reviewers, whereas data extraction was performed single reviewer. Eligible articles had to measure undertake internal or external validation. Tools recommended clinical implementation if they been externally found have ≥70%. Results The search strategy identified 3839 potential studies, which 236 progressed review 22 included. From these 50 predicted gastrointestinal/rectal symptoms, 29 genitourinary 4 erectile dysfunction, no quality life. For beam therapy, 3 could be rectal toxicity, gastrointestinal dysfunction. brachytherapy, urinary retention Conclusions A large number PROMs cancer developed. Only small minority are accurate shown generalizable This provides an accessible catalogue that ready as well should prioritized