Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells
作者： Shuai Han , Shaohua Yang , Zhai Cai , Dongyue Pan , Zhou Li
DOI: 10.2147/DDDT.S82342
关键词:
摘要: Background The Warburg effect refers to glycolytic production of adenosine triphosphate under aerobic conditions, and is a universal property most cancer cells. Chronic inflammation key factor promoting the effect. This study aimed determine whether rosmarinic acid (RA) has an anti-Warburg in gastric carcinoma vitro vivo. The mechanism for was also investigated.
sci-hub.se 参考文章(33)
Joana Gordo, Patrícia Máximo, Eurico Cabrita, Ana Lourenço, Abel Oliva, Joana Almeida, Mariana Filipe, Pedro Cruz, Rita Barcia, Miguel Santos, Helder Cruz, Thymus mastichina: chemical constituents and their anti-cancer activity. Natural Product Communications. ,vol. 7, pp. 1491- 1494 ,(2012) , 10.1177/1934578X1200701120
Daniel G. Rosen, Imelda Mercado-Uribe, Gong Yang, Robert C. Bast, Hesham M. Amin, Raymond Lai, Jinsong Liu, The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis Cancer. ,vol. 107, pp. 2730- 2740 ,(2006) , 10.1002/CNCR.22293
Jianqiang Liu, Jun Gao, Yiqi Du, Zhaoshen Li, Yan Ren, Junjun Gu, Xiaowei Wang, Yanfang Gong, Weiwei Wang, Xiangyu Kong, Combination of plasma microRNAs with serum CA19-9 for early detection of pancreatic cancer International Journal of Cancer. ,vol. 131, pp. 683- 691 ,(2012) , 10.1002/IJC.26422
Arvind Sahu, Nenoo Rawal, Michael K. Pangburn, Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b. Biochemical Pharmacology. ,vol. 57, pp. 1439- 1446 ,(1999) , 10.1016/S0006-2952(99)00044-1
Andrew H. Miller, Vladimir Maletic, Charles L. Raison, Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression Biological Psychiatry. ,vol. 65, pp. 732- 741 ,(2009) , 10.1016/J.BIOPSYCH.2008.11.029
Jean-Jacques Body, Effectiveness and cost of bisphosphonate therapy in tumor bone disease Cancer. ,vol. 97, pp. 859- 865 ,(2003) , 10.1002/CNCR.11139
D ISRAF, T KHAIZURIN, A SYAHIDA, N LAJIS, S KHOZIRAH, Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-κB nuclear translocation and Iκ-B phosphorylation in RAW 264.7 macrophage cells Molecular Immunology. ,vol. 44, pp. 673- 679 ,(2007) , 10.1016/J.MOLIMM.2006.04.025
Ke Shen, Qiannan Liang, Ke Xu, Daling Cui, Lin Jiang, Peihao Yin, Yanhua Lu, Qi Li, Jianwen Liu, MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor. Biochemical Pharmacology. ,vol. 84, pp. 320- 330 ,(2012) , 10.1016/J.BCP.2012.04.017
Gregg L. Semenza, Targeting HIF-1 for cancer therapy Nature Reviews Cancer. ,vol. 3, pp. 721- 732 ,(2003) , 10.1038/NRC1187
Shu-Feng Zhou, Chun-Xiu Yuan, Zhi-Wei Zhou, Yin-Xue Yang, Zhi-Xu He, Xueji Zhang, Dong Wang, Tianxin Yang, Ning-Ju Wang, Ruan Jin Zhao, Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells Drug Design Development and Therapy. ,vol. 9, pp. 487- 508 ,(2015) , 10.2147/DDDT.S74127