Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments : a WWARN individual patient data meta-analysis

Zenglei Wang, Yingna Wang, Mynthia Cabrera, Yanmei Zhang, Bhavna Gupta, Yanrui Wu, Karen Kemirembe, Yue Hu, Xiaoying Liang, Awtum Brashear, Sony Shrestha, Xiaolian Li, Jun Miao, Xiaodong Sun, Zhaoqing Yang, Liwang Cui, Artemisinin Resistance at the China-Myanmar Border and Association with Mutations in the K13 Propeller Gene Antimicrobial Agents and Chemotherapy. ,vol. 59, pp. 6952- 6959 ,(2015) , 10.1128/AAC.01255-15

Roland A. Cooper, Melissa D. Conrad, Quentin D. Watson, Stephanie J. Huezo, Harriet Ninsiima, Patrick Tumwebaze, Samuel L. Nsobya, Philip J. Rosenthal, Lack of artemisinin resistance in Plasmodium falciparum in Uganda based on parasitological and molecular assays Antimicrobial Agents and Chemotherapy. ,vol. 59, pp. 5061- 5064 ,(2015) , 10.1128/AAC.00921-15

L. K. Basco, Methods and techniques for assessing exposure to antimalarial drugs in clinical field studies. Methods and techniques for assessing exposure to antimalarial drugs in clinical field studies.. ,(2011)

Olivo Miotto, Roberto Amato, Elizabeth A Ashley, Bronwyn MacInnis, Jacob Almagro-Garcia, Chanaki Amaratunga, Pharath Lim, Daniel Mead, Samuel O Oyola, Mehul Dhorda, Mallika Imwong, Charles Woodrow, Magnus Manske, Jim Stalker, Eleanor Drury, Susana Campino, Lucas Amenga-Etego, Thuy-Nhien Nguyen Thanh, Hien Tinh Tran, Pascal Ringwald, Delia Bethell, Francois Nosten, Aung Pyae Phyo, Sasithon Pukrittayakamee, Kesinee Chotivanich, Char Meng Chuor, Chea Nguon, Seila Suon, Sokunthea Sreng, Paul N Newton, Mayfong Mayxay, Maniphone Khanthavong, Bouasy Hongvanthong, Ye Htut, Kay Thwe Han, Myat Phone Kyaw, Md Abul Faiz, Caterina I Fanello, Marie Onyamboko, Olugbenga A Mokuolu, Christopher G Jacob, Shannon Takala-Harrison, Christopher V Plowe, Nicholas P Day, Arjen M Dondorp, Chris C A Spencer, Gilean McVean, Rick M Fairhurst, Nicholas J White, Dominic P Kwiatkowski, Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nature Genetics. ,vol. 47, pp. 226- 234 ,(2015) , 10.1038/NG.3189

Kesinee Chotivanich, Rupam Tripura, Debashish Das, Poravuth Yi, Nicholas P. J. Day, Sasithon Pukrittayakamee, Char Meng Chuor, Duong Socheat, Arjen M. Dondorp, Nicholas J. White, Laboratory Detection of Artemisinin-Resistant Plasmodium falciparum Antimicrobial Agents and Chemotherapy. ,vol. 58, pp. 3157- 3161 ,(2014) , 10.1128/AAC.01924-13

Delia Bethell, Youry Se, Chanthap Lon, Stuart Tyner, David Saunders, Sabaithip Sriwichai, Sea Darapiseth, Paktiya Teja-Isavadharm, Phisit Khemawoot, Kurt Schaecher, Wiriya Ruttvisutinunt, Jessica Lin, Worachet Kuntawungin, Panita Gosi, Ans Timmermans, Bryan Smith, Duong Socheat, Mark M. Fukuda, Artesunate Dose Escalation for the Treatment of Uncomplicated Malaria in a Region of Reported Artemisinin Resistance: A Randomized Clinical Trial PLoS ONE. ,vol. 6, pp. e19283- ,(2011) , 10.1371/JOURNAL.PONE.0019283

Peter Starzengruber, Paul Swoboda, Hans-Peter Fuehrer, Wasif A. Khan, Verena Hofecker, Anja Siedl, Markus Fally, Oliver Graf, Paktiya Teja-Isavadharm, Rashidul Haque, Pascal Ringwald, Harald Noedl, Current Status of Artemisinin-Resistant falciparum Malaria in South Asia: A Randomized Controlled Artesunate Monotherapy Trial in Bangladesh PLoS ONE. ,vol. 7, pp. e52236- ,(2012) , 10.1371/JOURNAL.PONE.0052236

Kasia Stepniewska, Elizabeth Ashley, Sue J Lee, Nicholas Anstey, Karen I Barnes, Tran Quang Binh, Umberto D'Alessandro, Nicholas PJ Day, Peter J De Vries, Grant Dorsey, Jean-Paul Guthmann, Mayfong Mayxay, Paul N Newton, Piero Olliaro, Lyda Osorio, Ric N Price, Mark Rowland, Frank Smithuis, Walter RJ Taylor, François Nosten, Nicholas J White, None, In vivo parasitological measures of artemisinin susceptibility. The Journal of Infectious Diseases. ,vol. 201, pp. 570- 579 ,(2010) , 10.1086/650301

J. Straimer, N. F. Gnadig, B. Witkowski, C. Amaratunga, V. Duru, A. P. Ramadani, M. Dacheux, N. Khim, L. Zhang, S. Lam, P. D. Gregory, F. D. Urnov, O. Mercereau-Puijalon, F. Benoit-Vical, R. M. Fairhurst, D. Menard, D. A. Fidock, K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates Science. ,vol. 347, pp. 428- 431 ,(2015) , 10.1126/SCIENCE.1260867

E. Kamau, S. Campino, L. Amenga-Etego, E. Drury, D. Ishengoma, K. Johnson, D. Mumba, M. Kekre, W. Yavo, D. Mead, M. Bouyou-Akotet, T. Apinjoh, L. Golassa, M. Randrianarivelojosia, B. Andagalu, O. Maiga-Ascofare, A. Amambua-Ngwa, P. Tindana, A. Ghansah, B. MacInnis, D. Kwiatkowski, A. A. Djimde, K13-Propeller Polymorphisms in Plasmodium falciparum Parasites From Sub-Saharan Africa The Journal of Infectious Diseases. ,vol. 211, pp. 1352- 1355 ,(2014) , 10.1093/INFDIS/JIU608