Transposon system and methods of use
作者： Aron M. Geurts , Adam J. Dupuy , Geyi Liu , Karl J. Clark , Perry B. Hackett
DOI:
关键词:
摘要: The present invention is directed to improved transposons and transposases. also includes gene transfer systems, methods of using the transposases, compositions including
lens.org参考文章(313)
Anders H. Lund, Geoffrey Turner, Alla Trubetskoy, Els Verhoeven, Ellen Wientjens, Danielle Hulsman, Robert Russell, Ronald A. DePinho, Jack Lenz, Maarten van Lohuizen, Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice Nature Genetics. ,vol. 32, pp. 160- 165 ,(2002) , 10.1038/NG956
Annabeth Fieck, Denise L. Wyborski, Jay M. Short, Modifications of the E.coli Lac repressor for expression in eukaryotic cells: effects of nuclear signal sequences on protein activity and nuclear accumulation Nucleic Acids Research. ,vol. 20, pp. 1785- 1791 ,(1992) , 10.1093/NAR/20.7.1785
W. L. Lam, T. S. Lee, W. Gilbert, Active transposition in zebrafish Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 10870- 10875 ,(1996) , 10.1073/PNAS.93.20.10870
Ronald H.A Plasterk, Zsuzsanna Izsvák, Zoltán Ivics, Resident aliens: the Tc1/mariner superfamily of transposable elements. Trends in Genetics. ,vol. 15, pp. 326- 332 ,(1999) , 10.1016/S0168-9525(99)01777-1
B. T. Kren, B. Parashar, P. Bandyopadhyay, N. R. Chowdhury, J. R. Chowdhury, C. J. Steer, Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 10349- 10354 ,(1999) , 10.1073/PNAS.96.18.10349
Sean D. Colloms, Henri G.A.M. van Luenen, Ronald H.A. PIasterk, DNA binding activities of the Caenorhabditis elegans Tc3 transposase Nucleic Acids Research. ,vol. 22, pp. 5548- 5554 ,(1994) , 10.1093/NAR/22.25.5548
Andrea D. Converse, Lalitha R. Belur, Jennifer L. Gori, Geyi Liu, Felipe Amaya, Estuardo Aguilar-Cordova, Perry B. Hackett, R. Scott McIvor, Counterselection and Co-Delivery of Transposon and Transposase Functions for Sleeping Beauty -Mediated Transposition in Cultured Mammalian Cells Bioscience Reports. ,vol. 24, pp. 577- 594 ,(2004) , 10.1007/S10540-005-2793-9
Andrew M. Borman, Jean-Luc Bailly, Marc Girard, Katherine M. Kean, Picornavirus internal ribosome entry segments: comparison of translation efficiency and the requirements for optimal internal initiation of translation in vitro Nucleic Acids Research. ,vol. 23, pp. 3656- 3663 ,(1995) , 10.1093/NAR/23.18.3656
Koichi Kawakami, Akihiro Shima, Identification of the Tol2 transposase of the medaka fish Oryzias latipes that catalyzes excision of a nonautonomous Tol2 element in zebrafish Danio rerio. Gene. ,vol. 240, pp. 239- 244 ,(1999) , 10.1016/S0378-1119(99)00444-8
A. Alex Szekely, R. C. Woodruff, R. Mahendran, P element mediated germ line transformation of Drosophila melanogaster with the Tc1 transposable DNA element from Caenorhabditis elegans. Genome. ,vol. 37, pp. 356- 366 ,(1994) , 10.1139/G94-051