Direct expression of antibodies
作者： Andrew Geall , Todd Suscovich , Galit Alter
DOI:
关键词:
摘要: The present invention relates to methods exogenous nucleic acid molecules, such as RNA, that encode an antibody or antigen-binding fragment of antibody, and optionally a cellular modulation factor and/or potentiation factor. is results in increased expression the fragment. provides desired effector other properties. molecules can be DNA mRNA (including self-replication RNA non- self- replicating RNA). also method for administering subject achieve production encoded provide, example, prophylactic therapeutic passive immunity.
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