Vitamin E. Biological and environmental antioxidant

作者: Daniel B. Menzel , Jeffery N. Roehm , Si Duc Lee

DOI: 10.1021/JF60181A039

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摘要: Rats fed a diet high in unsaturated fatty acids (more susceptible to oxidation) were exposed O/sub 3/ or NO/sub 2/. Vitamin E decreased acute toxicity from 2/; LT/sub 50/ for tocopherol-depleted rats 1.5 ppM was 8.2 days compared with 18.5 those supplementation. Those figures 33 2/ 11.1 vs 17 days. 0.5 accelerated depletion of vitamin erythrocytes. Oxidant stress also evidenced by lower serum glutathione and tissue sulfhydryl content. oleic linoleic acid content but increased arachidonic

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