The use and safety of Ibuprofen in the hemophiliac.

摘要: After demonstrating initial safety of Ibuprofen administered to hemophiliacs, a 16-wk double-blind individual crossover trial was designed test the and, more limited extent, efficacy 1600 mg or placebo given daily 20 hemophiliacs with hemophiliac arthropathy. The completed no evidence increased frequency severity bleeding episodes clinical laboratory secondary Ibuprofen. There were five treatment failures, none associated hemorrhage lack compliance. A benefit obtained in reduction early morning stiffness and pain. should be considered as safe potentially beneficial antiinflammatory agent carefully monitored eligible for such therapy.