Neuritic outgrowth from goldfish retinal explants, interaction of taurine and zinc.
作者： Sonia Nusetti , Francisco Obregón , Lucimey Lima
DOI: 10.1007/978-0-387-33504-9_50
关键词:
摘要: Various studies provide evidence for an interaction between taurine and zinc during development, affecting the morphology function of retina. The objectives present work were to determine levels in retina goldfish regeneration investigate effect intracellular chelator N,N,N,N-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) on trophic role outgrowth from post-crush retinal explants. Taurine was determined by HPLC (nmol/mg protein) spectrophotometry ICP (µg/mg at various days post-crushing optic nerve. significantly increased 72 h 24 h. Explants retinas, 10 post-crush, cultured 5 presence concentrations combinations TPEN taurine. TPEN, 1 nM, decreased but simultaneously with (1–8 mM) there increase. These results demonstrate that necessary normal fibers counteracted effect.
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