Genome-wide characterization of coding and non-coding RNAs in the ovary of honeybee workers and queens

摘要: Adult honeybee queens and workers drastically differ in ovary state size. However, this reproductive bias is only partially understood from the view of a single RNA type. In study, we predicted 10,271 mRNAs, 7235 lncRNAs, 11,794 circRNAs, 164 miRNAs through bioinformatics. Combining sequencing data virgin queens, 4385 2390 5602 75 were differentially expressed compared with virgins. Compared egg-laying 6536 3130 5751 81 workers. Further, functional annotation revealed that neural regulation was closely related to state. Moreover, potential interactions among miRNAs, mRNAs vitellogenin, ecdysone-induced protein 74, ame_circ_0001176, ame_circ_0001243 might play critical roles competing endogenous network. These findings suggest integrative networks have effects ovarian phenotype differences honeybees.