The Gap between Estimated Incidence of End-Stage Renal Disease and Use of Therapy

摘要: Background: Relatively few data exist on the burden of end-stage renal disease (ESRD) and use replacement therapy (RRT)–a life-saving therapy–in developing regions. No study has quantified proportion patients who develop ESRD but are unable to access RRT. Methods: We performed a comprehensive literature search estimate annual initiation RRT worldwide, present these estimates according World Bank also survival etiology diseases in undergoing Using prevalence diabetes hypertension, we modeled incidence related risk factors order quantify gap between Results: find that 1.9 million with continued at 316 73 per population respectively. correlates directly (Pearson’s r=0.94) regional income. Hemodialysis remains dominant form there is wide variation its use. With exception Latin American Caribbean region, it appears regions restricted fewer than quarter projected ESRD. This results least 1.2 premature deaths each year due lack as result elevated blood pressure many 3.2 all causes Conclusion: Thus, majority reach or hypertension RRT; this will increase rising worldwide.