Computed Tomography–Navigated Transthoracic Core Biopsy of Pulmonary Lesions

摘要: Rationale and Objectives Only a few studies have systematically evaluated risk factors for pneumothorax pulmonary hemorrhage in computed tomographically (CT)-guided transthoracic lung biopsy (TLB). We the diagnostic yield of CT-guided TLB determined hemorrhage. Methods One hundred seventy-two TLBs were performed on 159 patients (mean age 66 ± 11 years; 72% male) using 16-gauge core needle. Lesion patient characteristics, function analysis, CT signs emphysema, histopathologic diagnoses, complications recorded. Statistical analysis was with multivariate regression analysis. Results Histopathologic diagnosis established 153 cases (89%). Although lesion size higher (47 29 vs. 43 35 mm, P = .191) depth lower (22 23 6 23mm, .350) procedures diagnosis, no parameter showed significant impact yield. Sensitivity specificity detection malignancy 93% 100%, respectively, whereas positive negative predictive values 100% 88%. Overall accuracy 95%. Pneumothorax occurred 45 (26%). Hemorrhage recorded 17 (10%). There frequency smaller lesions (35 50 31 .003; odds ratio .96) greater (29 20 19 .05; 1.03). emphysema revealed incidence (35% 23%; .04; ratio=41.03). Other parameters nonsignificant. Conclusions The high not affected by characteristics or emphysema. rate influenced depth. associated