Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.
作者： Mark E. Gurney , Frank B. Cutting , Ping Zhai , Adam Doble , Charles P. Taylor
关键词:
摘要: … , has been linked to neuronal damage in acute illnesses such … We sought to restore brain vitamin E levels in GIN/+ and GILI… Lipid peroxidation is opposed by vitamin E and is implicated …
sci-hub.se 参考文章(57)
R. M. Garruto, M. Yasui, Y. Yase, K. Ota, Aluminum deposition in the central nervous system of patients with amyotrophic lateral sclerosis from the Kii Peninsula of Japan. Neurotoxicology. ,vol. 12, pp. 615- 620 ,(1991)
M. C. Dal Canto, M. E. Gurney, Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. American Journal of Pathology. ,vol. 145, pp. 1271- 1279 ,(1994)
Troy T. Rohn, Thomas R. Hinds, Frank F. Vincenzi, Ion transport ATPases as targets for free radical damage: Protection by an aminosteroid of the Ca2+ pump atpase and Na+/K+ pump ATPase of human red blood cell membranes Biochemical Pharmacology. ,vol. 46, pp. 525- 534 ,(1993) , 10.1016/0006-2952(93)90530-A
Christiane Malgouris, Marc Daniel, Adam Doble, Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices. Neuroscience Letters. ,vol. 177, pp. 95- 99 ,(1994) , 10.1016/0304-3940(94)90053-1
Philip G. Reeves, Forrest H. Nielsen, George C. Fahey, AIN-93 Purified Diets for Laboratory Rodents: Final Report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet Journal of Nutrition. ,vol. 123, pp. 1939- 1951 ,(1993) , 10.1093/JN/123.11.1939
T Hebert, L Pradier, P Drapeau, R J Dunn, Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole. Molecular Pharmacology. ,vol. 45, pp. 1055- 1060 ,(1994)
David Martin, Michael A. Thompson, J.Victor Nadler, The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. European Journal of Pharmacology. ,vol. 250, pp. 473- 476 ,(1993) , 10.1016/0014-2999(93)90037-I
Arie Goldlust, Ti-Zhi Su, Devin F. Welty, Charles P. Taylor, Dale L. Oxender, Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA Epilepsy Research. ,vol. 22, pp. 1- 11 ,(1995) , 10.1016/0920-1211(95)00028-9
Jeffrey D. Rothstein, Lee J. Martin, Ralph W. Kuncl, Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis The New England Journal of Medicine. ,vol. 326, pp. 1464- 1468 ,(1992) , 10.1056/NEJM199205283262204
P B McCay, Vitamin E: Interactions with Free Radicals and Ascorbate Annual Review of Nutrition. ,vol. 5, pp. 323- 340 ,(1985) , 10.1146/ANNUREV.NU.05.070185.001543