C-reactive protein comes of age

摘要: Cardiovascular disease remains a leading cause of death throughout the world despite advances in its detection and treatment. Commonly used risk algorithms, such as Framingham Risk Score fail to identify all affected individuals. Novel cardiovascular factors that these missed individuals would greatly improve overall care patients. C-reactive protein (CRP), an inflammatory biomarker, has emerged candidate fulfill this role. Based on results several prospective epidemiologic studies, CRP one most powerful predictors disease. This marker provides valuable information clinicians various clinical settings, ranging from overt disease, stable angina, presenting acute coronary syndromes peripheral vascular metabolic syndrome. Furthermore, been demonstrated actively contribute stages atherogenesis, participating endothelial dysfunction, atherosclerotic-plaque formation, plaque maturation, destabilization eventual rupture. Thus, it might also serve therapeutic target. It is our contention future will see much wider use CRP-driven therapies medicine, improving ability manage