Improved free energies for G.C base-pairs.

作者: Susan M. Freier , Alison Sinclair , Thomas Neilson , Douglas H. Turner

DOI: 10.1016/0022-2836(85)90077-4

关键词:

摘要: Thermodynamic parameters of helix formation are reported for seven oligoribonucleotides containing only G · C pairs. These data used with the nearest-neighbor model to calculate enthalpies and free energies base-pair For initiation, energy change at 37 °C, ΔG370, is + 3.9 kcal/mol; propagation, ΔG370 values −2.3, −3.2 −3.3 kcal/mol C-G, G-G G-C neighbors, respectively.

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