Respiratory distress management in moderate and late preterm infants: The NEOBS Study.

摘要: Abstract Objective To investigate the characteristics and management of respiratory failure (RF) in moderate-to-late preterm infants. Methods NEOBS was a prospective, multicenter, observational study conducted 46 neonatal intensive care units caring for infants (30 + 0/7 to 36 + 6/7 weeks gestation [WG]) France 2018. The cohort stratified into two groups: 30–33 WG (group 1) 34–36 2). Infants with early RF were included outcomes assessed maternal, pregnancy, delivery how managed. Results Of 560 analyzed, 279 group 1 281 2. Most pregnancies singleton (64.1%), 67.4% women received prenatal corticosteroids (mostly doses). delivered by cesarean section 59.6% cases; 91.7% had an Apgar score ≥ 7 at 5 min. More than 90% hospitalized post-birth (median duration, 36 15 days groups 2, respectively). Medical intervention required 95.7% 90.4% respectively, noninvasive ventilation (continuous positive airway pressure [CPAP]: 88.5% 82.9%; high-flow nasal cannula: 55.0% 44.7%, or other) invasive (19.7% 13.2%). main diagnoses distress syndrome (39.8%) transient tachypnea newborn (57.3%). Surfactant administered 22.5% infants, using less surfactant administration (LISA) method 34.4% patients. In overall population, 8.6% and/or hemodynamic complications. Conclusions demonstrated that CPAP widely used room LISA chosen administrations incidence RF-related complications low.