Immunonutrition in Critical Illness: What Is the Role?

摘要: Acute illness-associated malnutrition leads to muscle wasting, delayed wound healing, failure wean from ventilator support, and possibly higher rates of infection longer hospital stays unless appropriate metabolic support is provided in the form nutrition therapy. Agreement still lacking about value individual immune-modulating substrates for specific patient populations. However, it has long been agreed that there are 3 primary targets these substrates: 1) mucosal barrier function, 2) cellular defense 3) local systemic inflammation. These guide multitude interventions necessary stabilize treat hypercatabolic intensive care unit patient, including specialized The paradigm shift occurred 30 years ago created a unique role as an agent host mechanisms prevent infectious complications critically ill patient. This overview immunonutrition will discuss evidence its critical illness today.