The role of polyglutamine aggregate cytotoxicity in Huntington’s Disease

作者: Wen Yang

DOI:

关键词:

摘要:

参考文章(230)
Sue E. Slezak, Paul Karl Horan, Cell-mediated cytotoxicity: A highly sensitive and informative flow cytometric assay Journal of Immunological Methods. ,vol. 117, pp. 205- 214 ,(1989) , 10.1016/0022-1759(89)90142-7
P. Hemachandra Reddy, Maya Williams, Vinod Charles, Lisa Garrett, Lisa Pike-Buchanan, William O. Whetsell, Georgina Miller, Danilo A. Tagle, Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA Nature Genetics. ,vol. 20, pp. 198- 202 ,(1998) , 10.1038/2510
John P. Jakupciak, Robert D. Wells, Genetic Instabilities in (CTG·CAG) Repeats Occur by Recombination Journal of Biological Chemistry. ,vol. 274, pp. 23468- 23479 ,(1999) , 10.1074/JBC.274.33.23468
Victor O. Ona, Mingwei Li, Jean Paul G. Vonsattel, L. John Andrews, Sohail Q. Khan, Woosik M. Chung, Ariel S. Frey, Anil S. Menon, Xiao-Jiang Li, Philip E. Stieg, Junying Yuan, John B. Penney, Anne B. Young, Jang-Ho J. Cha, Robert M. Friedlander, Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease Nature. ,vol. 399, pp. 263- 267 ,(1999) , 10.1038/20446
John M. Warrick, H.Y. Edwin Chan, Gladys L. Gray-Board, Yaohui Chai, Henry L. Paulson, Nancy M. Bonini, Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nature Genetics. ,vol. 23, pp. 425- 428 ,(1999) , 10.1038/70532
Irina V. Kovtun, Cynthia T. McMurray, Trinucleotide expansion in haploid germ cells by gap repair Nature Genetics. ,vol. 27, pp. 407- 411 ,(2001) , 10.1038/86906
Duong P. Huynh, Karla Figueroa, Nam Hoang, Stefan-M. Pulst, Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human. Nature Genetics. ,vol. 26, pp. 44- 50 ,(2000) , 10.1038/79162
Guillermo Orozco, Rafael Estrada, Thomas L. Perry, Julian Araña, Rebecca Fernandez, Alina Gonzalez-Quevedo, Joaquin Galarraga, Shirley Hansen, Dominantly inherited olivopontocerebellar atrophy from eastern Cuba. Clinical, neuropathological, and biochemical findings. Journal of the Neurological Sciences. ,vol. 93, pp. 37- 50 ,(1989) , 10.1016/0022-510X(89)90159-7