Inadequate Cardioplegic Protection with Obstructed Coronary Arteries

摘要: Abstract To determine the contribution of complete cardioplegia to preservation left ventricular (LV) function, we put ultrasonic transducers in anterior and posterior walls ventricle 18 dog hearts. The dogs were subjected global ischemia for 60 minutes at 28°C, speed segment shortening (dl/dt) percent systolic two wall regions before after ischemic manipulations measured. When cardioplegic perfusion was uniform, there no significant difference between any variables measured, LV function (stroke work) well preserved. However, when descending coronary artery occluded during infusion, dysfunction reperfusion wall: without perfusion, segments recovered only 41% (5.9/14.3 mm/sec) preischemic dl/dt, while perfused retained 78% (11.4/14.6 control dl/dt ( p Regionally inadequate protection bypass graft operation may contribute perioperative infarction dysfunction, appropriate timing anastomoses ensure early all myocardium is important.