Fibrillary astrocytes proliferate in response to brain injury: A study combining immunoperoxidase technique for glial fibrillary acidic protein and radioautography of tritiated thymidine

作者: Norman Latov , Gajanan Nilaver , Earl A. Zimmerman , William G. Johnson , Ann-Judith Silverman

DOI: 10.1016/0012-1606(79)90127-1

关键词:

摘要: Abstract To determine whether fibrillary astrocytes proliferate in response to brain injury, cells identified as using immunoperoxidase technique for glial acidic protein (GFAP) were examined uptake of radiolabeled thymidine by autoradiography. In injured mouse brain, autoradiographic label was present over nuclei immunoreactive the lesion site 1 hr following injection thymidine. The data suggest that which are sufficiently differentiated accumulate GFAP retain capacity injury.

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