Two new triterpene and a new nortriterpene glycosides from Phlomis viscosa

摘要: The isolation and structure elucidation of two new oleanane-type triterpene glycosides, 29-(β-D-glucopyranosyloxy)-2α,3β,23-trihydroxyolean-12-en-28-oic acid (=(2α,3β,4α,29α)-29-(β-D-glucopyranosyloxy)-2,3,23-trihydroxyolean-12-en-28-oic acid; 1) its C(20)-epimer, 30-(β-D-glucopyranosyloxy)-2α,3β,23-trihydroxyolean-12-en-28-oic (=(2α,3β,4α,29β)-29-β-D-glucopyranosyloxy)-2,3,23-trihydroxyolean-12-en-28-oic 2), a novel nortriterpene glycoside, (17S)-2α,18β,23-trihydroxy-3,19-dioxo-19(18[RIGHTWARDS ARROW]17)- abeo-28-norolean-12-en-25-oic β-D-glucopyranosyl ester (=(1R,2S,4aS,4bR,6aR,7R,9R,10aS,10bS)-3,4,4a,4b,5,6,6a,7,8,9,10,10a,10b,11-tetradecahydro-1-hydroxy-7-(hydroxymethyl)-3′,4′,4a,4b,7-pentamethyl-2′,8- dioxospiro[chrysene-2(1H),1′-cyclopentane]-10a-carboxylic ester; 3) from Phlomis viscosa (Lamiaceae) are reported. structures the compounds were asigned by means spectroscopic (IR, 1D- 2D-NMR, LC-ESI-MS) chemical (acetylation) methods.