作者: David S. Jones , Clare P. Garvin , Denis Dowling , Kevin Donnelly , Sean P. Gorman
DOI: 10.1002/JBM.B.30474
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摘要: Despite the emerging use of diamond-like carbon (DLC) as a coating for medical devices, few studies have examined resistance DLC coatings onto polymers to both microbial adherence and encrustation. In this study, amorphous range refractive indexes (1.7-1.9) thicknesses (100-600 nm) was deposited polyurethane, model polymer, (Escherichia coli; clinical isolate) encrustation using in vitro models. comparison native advancing receding contact angles DLC-coated polyurethane were lower, indicating greater hydrophilic properties. No relationship observed between index, thickness, angle, determined multiple correlation analysis. The resistances various films significantly than that polyurethane; however, there individual differences coatings. general, increasing index (100 nm thickness) decreased hydroxyapatite struvite adherence. Films lower 200 nm; defined 1.8), exhibited greatest conclusion, study has uniquely illustrated antiadherence properties urinary polyurethane. substantial, light this, it is suggested low thickness show particular promise polymeric devices.