Prokaryotic chromosomes and disease.

作者: Jorg Hacker , Ute Hentschel , Ulrich Dobrindt

DOI: 10.1126/SCIENCE.1086802

关键词:

摘要: Recent insights into bacterial genome organization and function have improved our understanding of the nature pathogenic bacteria their ability to cause disease. It is becoming increasingly clear that chromosome constantly undergoes structural changes due gene acquisition loss, recombination, mutational events an impact on potential bacterium. Even though includes additional genetic elements, represents most important entity in this context. Here, we will show various processes genomic instability influence many manifestations infectious

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