Class II genes of the human major histocompatibility complex. The DO beta gene is a divergent member of the class II beta gene family.
作者： B Servenius , L Rask , P A Peterson
DOI: 10.1016/S0021-9258(18)47481-9
关键词:
摘要: A novel class II beta chain gene is described. This gene, tentatively called DO beta, displays considerably less polymorphism than genes of the DP, DQ, and DR loci. The nucleotide sequence strikingly similar to that previously identified murine 2 gene. same exon/intron organization as other although fifth exon translated portion sixth are longer in genes. striking feature amino acid deduced from pronounced hydrophobicity NH2-terminal region. distinguishes putative chains raises possibility may interact with an alpha structurally different those It further suggests molecule have a function antigens.
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