[Stem cells from fatty tissue : A new resource for regenerative medicine?].
作者： B Weyand , J W Kuhbier , K Reimers , C Radtke , H Sorg
DOI: 10.1007/S00104-010-1962-Y
关键词:
摘要: While stem cells derived from the bone marrow are well-known in clinical medicine, fatty tissue as a source of mesenchymal is still subject recent research. However, adipose-derived (ASC) not only harvested less invasively, i.e. via minimally invasive liposuction, but also yield higher numbers multipotent cells.Due to cell-cell interactions and because very favorable secretion profile growth factors cytokines ASCs displayed an extraordinary regenerative potential preclinical applications achieved significantly better healing ischemic muscle, heart, brain insults impaired wound healing. enhanced regeneration skeletal tissues such cartilage or bone. They revealed immunomodulatory effects improved status immunological diseases.In conclusion comparable marrow-derived concerning possible medicine.
sci-hub.st 参考文章(27)
Cheng-Yu Lv, Hai-Ning Zhang, Ying-Zhen Wang, Ping Leng, Lei Li, Uninduced adipose-derived stem cells repair the defect of full-thickness hyaline cartilage. Chinese Journal of Traumatology (english Edition). ,vol. 12, pp. 92- 97 ,(2009) , 10.3760/CMA.J.ISSN.1008-1275.2009.02.006
Jörn W. Kuhbier, Birgit Weyand, Christine Radtke, Peter M. Vogt, Cornelia Kasper, Kerstin Reimers, Isolation, characterization, differentiation, and application of adipose-derived stem cells. Advances in Biochemical Engineering \/ Biotechnology. ,vol. 123, pp. 55- 105 ,(2010) , 10.1007/10_2009_24
Manuel A. González, Elena Gonzalez-Rey, Laura Rico, Dirk Büscher, Mario Delgado, Treatment of experimental arthritis by inducing immune tolerance with human adipose‐derived mesenchymal stem cells Arthritis & Rheumatism. ,vol. 60, pp. 1006- 1019 ,(2009) , 10.1002/ART.24405
B. Fang, Y. Song, L. Liao, Y. Zhang, R.C. Zhao, Favorable Response to Human Adipose Tissue-Derived Mesenchymal Stem Cells in Steroid-Refractory Acute Graft-Versus-Host Disease Transplantation Proceedings. ,vol. 39, pp. 3358- 3362 ,(2007) , 10.1016/J.TRANSPROCEED.2007.08.103
John K. Fraser, Isabella Wulur, Zeni Alfonso, Marc H. Hedrick, Fat tissue: an underappreciated source of stem cells for biotechnology Trends in Biotechnology. ,vol. 24, pp. 150- 154 ,(2006) , 10.1016/J.TIBTECH.2006.01.010
Yusuke Sakaguchi, Ichiro Sekiya, Kazuyoshi Yagishita, Takeshi Muneta, Comparison of human stem cells derived from various mesenchymal tissues: Superiority of synovium as a cell source Arthritis & Rheumatism. ,vol. 52, pp. 2521- 2529 ,(2005) , 10.1002/ART.21212
Stefan Lendeckel, Andreas Jödicke, Petros Christophis, Kathrin Heidinger, Jan Wolff, John K. Fraser, Marc H. Hedrick, Lars Berthold, Hans-Peter Howaldt, Autologous stem cells (adipose) and fibrin glue used to treat widespread traumatic calvarial defects: case report Journal of Cranio-maxillofacial Surgery. ,vol. 32, pp. 370- 373 ,(2004) , 10.1016/J.JCMS.2004.06.002
B Fang, Y P Song, L M liao, Q Han, R C Zhao, Treatment of severe therapy-resistant acute graft-versus-host disease with human adipose tissue-derived mesenchymal stem cells. Bone Marrow Transplantation. ,vol. 38, pp. 389- 390 ,(2006) , 10.1038/SJ.BMT.1705457
Won-Serk Kim, Byung-Soon Park, Hyung-Ki Kim, Jeong-Soo Park, Kea-Jeung Kim, Joon-Seok Choi, Suk-Jae Chung, Dae-Duk Kim, Jong-Hyuk Sung, Evidence supporting antioxidant action of adipose-derived stem cells: Protection of human dermal fibroblasts from oxidative stress Journal of Dermatological Science. ,vol. 49, pp. 133- 142 ,(2008) , 10.1016/J.JDERMSCI.2007.08.004
Jalees Rehman, Dmitry Traktuev, Jingling Li, Stephanie Merfeld-Clauss, Constance J. Temm-Grove, Jason E. Bovenkerk, Carrie L. Pell, Brian H. Johnstone, Robert V. Considine, Keith L. March, Secretion of Angiogenic and Antiapoptotic Factors by Human Adipose Stromal Cells Circulation. ,vol. 109, pp. 1292- 1298 ,(2004) , 10.1161/01.CIR.0000121425.42966.F1