Research on opioid substitution therapy in India: A brief, narrative review

摘要: Opioid dependence is a significant clinical and public health issue in India. substitution therapy (OST) the most evidence-based treatment for opioid dependence. Although available India about three decades now, Indian research on this modality has not been adequately reviewed so far. We conducted narrative review of OST. an online search relevant literature peer-reviewed journals as well general books monographs. present findings form description according to certain identified themes. Considering that methadone became India, only recently, OST predominantly features buprenorphine agent. Effectiveness among opioid-dependent patients established through prospective, experimental designs naturalistic studies using retrospective, chart-review approach. Naturalistic observational postmarketing surveillance have demonstrated safety when used There are areas which more will be beneficial clinicians policy-makers. However, quantum evidence base exists than adequate justify scale-up treatment. A conducive policy environment scaling-up need hour.