Cognitive function in breast cancer survivors.

摘要: Cancer survivors have coined the terms ‘‘chemobrain’’ and ‘‘chemofog’’ to refer problems that patients experience with their memory and/or concentration during after completing chemotherapy. A number of studies confirmed some breast cancer suffer cognitive impairment chemotherapy [1–8], although recent found women’s may predate [9], hormonal treatment also impact on function [8, 10]. For most women problem appears subtle often improves ceasing chemotherapy; however, for a subset survivors, symptoms are sustained can significantly quality life ability in everyday activities [7, 11, 12]. Cognitive who received inconsistent describing types neuropsychological dysfunction found, commonly affected domains attention/concentration, verbal visual memory, processing speed [1–8, 13]. Similar been identified early stage human immunodeficiency virus (HIV) infection [14, 15], Huntington’s disease [16], Parkinson’s [17] multiple sclerosis [18]. In each these diseases, when occurs, it is generally subtle, ‘‘spotty’’ variable from one patient next 19]. neuropsychologists believe deficits more consistent sub-cortical abnormality 15, 20–23] as distinct cortical seen dementias. Age, intelligence quotient (IQ) education all factors influence [24, 25] corrected standard tests. Other variables affect function, particularly context diagnosis, but difficult correct