Racial and Ethnic Differences in Advanced-Stage Prostate Cancer: the Prostate Cancer Outcomes Study

摘要: Background: African-Americans have twice the risk of non-Hispanic whites for presenting with advanced-stage prostate cancer. To investigate reasons this difference, we evaluated association between race/ ethnicity and cancer, adjusting demographic, socioeconomic, clinical, pathologic factors. Methods: A population-based cohort 3173 men diagnosed cancer October 1, 1994, 31, 1995, was analyzed. Medical record abstracts self-administered survey questionnaires were used to obain information regarding race/ethnicity, age, marital status, insurance educational level, household income, employment comorbidity, urinary function, prostate-specific antigen tumor grade, clinical stage. The odds ratio (OR) estimated weighted logistic regression analysis. All P values two-sided. Results: Clinically cancers detected more frequently in (12.3%) Hispanics (10.5%) than (6.3%). Socioeconomic, factors each accounted about 15% increased relative risk. After all covariates, remained statistically significantly (OR = 2.26; 95% confidence interval [CI] 1.43 3.58) but not 1.23; CI 0.73 2.08). Conclusion: Traditional Hispanic African-American men.