Antioxidant ability of caffeine and its metabolites based on the study of oxygen radical absorbing capacity and inhibition of LDL peroxidation

作者: Chul Lee

DOI: 10.1016/S0009-8981(00)00201-1

关键词:

摘要: … The antioxidant activity was however significant with 1-methylxanthine (1-X) and 1-methyluric acid (1-U), the main metabolites of caffeine in humans. The relative ORAC values of Trolox…

参考文章(33)
T Chou, Wake up and smell the coffee. Caffeine, coffee, and the medical consequences. Western Journal of Medicine. ,vol. 157, pp. 544- 553 ,(1992)
K R Maples, R P Mason, Free radical metabolite of uric acid. Journal of Biological Chemistry. ,vol. 263, pp. 1709- 1712 ,(1988) , 10.1016/S0021-9258(19)77933-2
K.D.R. Setchell, Mary Beth Welsh, Marquelle J. Klooster, W.F. Balistreri, C.K. Lim, Rapid high-performance liquid chromatography assay for salivary and serum caffeine following an oral load Journal of Chromatography A. ,vol. 385, pp. 267- 274 ,(1987) , 10.1016/S0021-9673(01)94639-4
John A. Buege, Steven D. Aust, Microsomal lipid peroxidation. Methods in Enzymology. ,vol. 52, pp. 302- 310 ,(1978) , 10.1016/S0076-6879(78)52032-6
Franklin H. Epstein, Daniel Steinberg, Sampath Parthasarathy, Thomas E. Carew, John C. Khoo, Joseph L. Witztum, Beyond Cholesterol New England Journal of Medicine. ,vol. 320, pp. 915- 924 ,(1989) , 10.1056/NEJM198904063201407
Gordon C. Hard, Chi-Tang Ho, Mou Tuan Huang, Jian Guo Xie, Allan H. Conney, Zhi Yuan Wang, Zhi Yuan Wang, Chung Xiou Wang, You Rong Lou, Effects of tea, decaffeinated tea, and caffeine on UVB light-induced complete carcinogenesis in SKH-1 mice: demonstration of caffeine as a biologically important constituent of tea. Cancer Research. ,vol. 57, pp. 2623- 2629 ,(1997)
Robert J. DeLange, Alexander N. Glazer, Phycoerythrin fluorescence-based assay for peroxy radicals: a screen for biologically relevant protective agents. Analytical Biochemistry. ,vol. 177, pp. 300- 306 ,(1989) , 10.1016/0003-2697(89)90056-0
C H Ashton, Caffeine and health. BMJ. ,vol. 295, pp. 1293- 1294 ,(1987) , 10.1136/BMJ.295.6609.1293
A. Nishikawa, F. Furukawa, T. Imazawa, S. Ikezaki, T. Hasegawa, M. Takahashi, Effects of caffeine on glandular stomach carcinogenesis induced in rats by N-methyl-N′-nitro-N-nitrosoguanidine and sodium chloride Food and Chemical Toxicology. ,vol. 33, pp. 21- 26 ,(1995) , 10.1016/0278-6915(95)80243-6
Barry Halliwell, Free radicals and antioxidants: a personal view. Nutrition Reviews. ,vol. 52, pp. 253- 265 ,(2009) , 10.1111/J.1753-4887.1994.TB01453.X