Inhibitor of ribonucleotide reductase

作者: Victor M. Garsky , Robert A. Stein

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摘要: A series of oligopeptides each which contains a D-amino acid has been found to inhibit the activity ribonucleotide reductase enzyme herpes simplex virus in vitro thereby inhibiting viral replication.

参考文章(5)
Yves Langelier, Pierrette Gaudreau, Jacques Michaud, Eric A. Cohen, Paul Brazeau, Antiviral peptides and means for treating herpes infections ,(1987)
E. A. Cohen, P. Gaudreau, P. Brazeau, Y. Langelier, Specific inhibition of herpesvirus ribonucleotide reductase by a nonapeptide derived from the carboxy terminus of subunit 2. Nature. ,vol. 321, pp. 441- 443 ,(1986) , 10.1038/321441A0
Bernadette M. Dutia, Margaret C. Frame, John H. Subak-Sharpe, William N. Clark, Howard S. Marsden, Specific inhibition of herpesvirus ribonucleotide reductase by synthetic peptides Nature. ,vol. 321, pp. 439- 441 ,(1986) , 10.1038/321439A0
Frame Margaret Catherine, Clements John Barklie, Dutia Bernadette Mary, Marsden Howard Sinkinson, Subak-Sharpe John Herbert, Peptide inhibitor of ribonucleotide reductase ,(1987)