Diels-Alder routes to angularly halogenated cis-fused bicyclic ketones: Readily accessible cyclynone intermediates.
作者： Jun Hee Lee , Woo Han Kim , Samuel J. Danishefsky
DOI: 10.1016/J.TETLET.2010.06.135
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摘要: Abstract We have developed an efficient Lewis acid-catalyzed Diels–Alder route to a series of cis-fused bicyclic ketones bearing quaternary halogenation at the angular position. also Diels–Alder-based one-flask method for regioselective preparation TBS-protected 6-hydroxy tetralone and 5-hydroxy indanone derivatives.
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