Plants with neurotoxic potential in undernourished subjects

作者: V.S. Palmer , D.D. Tshala-Katumbay , P.S. Spencer

DOI: 10.1016/J.NEUROL.2019.07.015

关键词:

摘要: The consumption by humans of plants with potential to induce neurological disorders is widespread, but overt disease surfaces only when the subject's toxic threshold exceeded. Excessive intake arising from food dependency in setting hunger, chronic undernutrition, vitamin deficiency, inadequate detoxication, or other individual susceptibility, can trigger acute encephalopathy (lychee, ackee fruits), sub-acute spastic paraparesis (grasspea, cassava root/leaves) ataxic neuropathy (cassava root flour). While these are very rarely encountered high-income countries, they not common among impoverished populations also often occur as outbreaks that impact a significant proportion an affected community. Unfamiliarity adverse effects plant toxins has sometimes led mistaken attribution nutritional neurotoxic neurotropic viral synthetic pesticidal etiology. combination human population growth, and water insecurity, poverty and, climate change, increased on environmentally tolerant potential, predictably may result prevalence disorders, especially certain parts Africa Asia.

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