作者: Wayne J. Hawthorne , Lindy Williams , Yi Vee Chew
DOI: 10.1007/978-3-319-39824-2_7
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摘要: The overarching success of islet transplantation relies on the in laboratory to isolate islets. This chapter focuses processes human cell isolation and ways optimally provide cells for transplantation. major improvements regards choice enzyme type, way digested pancreas tissue is handled best separate islets from acinar surrounding tissues, various methods purification islets, their subsequent culture quality assurance improve outcomes culminate safe effective will be discussed. After decades improvements, now clearly offer a safe, feasible therapeutic treatment option an increasing number patients suffering type 1 diabetes specifically those with severe hypoglycaemic unawareness.