Enzymes as catalysts in synthesis of enantiomerically pure building blocks : secondary alcohols bearing two vicinal stereocenters
作者： Rong Liu
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摘要: Enzymes as tools in organic synthesis have provided enormous advantages. This thesis deals with the applications of enzymes kinetic resolutions racemic compounds. The stereochemistry c ...
参考文章(58)
Waldemar Adam, Frank Heckel, Chantu R Saha-Möller, Peter Schreier, Biocatalytic synthesis of optically active oxyfunctionalized building blocks with enzymes, chemoenzymes and microorganisms Journal of Organometallic Chemistry. ,vol. 661, pp. 17- 29 ,(2002) , 10.1016/S0022-328X(02)01805-3
Kyeong Kyu Kim, Hyun Kyu Song, Dong Hae Shin, Kwang Yeon Hwang, Se Won Suh, The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of a bound inhibitor. Structure. ,vol. 5, pp. 173- 185 ,(1997) , 10.1016/S0969-2126(97)00177-9
G. Bergström, A. -B. Wassgren, O. Anderbrant, J. Fägerhag, H. Edlund, E. Hedenström, H. -E. Högberg, C. Geri, M. A. Auger, M. Varama, B. S. Hansson, J. Löfqvist, Sex pheromone of the pine sawfly Diprion pini (Hymenoptera: Diprionidae) : Chemical identification, synthesis and biological activity Cellular and Molecular Life Sciences. ,vol. 51, pp. 370- 380 ,(1995) , 10.1007/BF01928898
K. Bagi, L.M. Simon, B. Szajáni, Immobilization and characterization of porcine pancreas lipase Enzyme and Microbial Technology. ,vol. 20, pp. 531- 535 ,(1997) , 10.1016/S0141-0229(96)00190-1
Bernard Testa, Chiral aspects of drug metabolism Trends in Pharmacological Sciences. ,vol. 7, pp. 60- 64 ,(1986) , 10.1016/0165-6147(86)90255-5
Ba-Vu Nguyen, Erik Hedenström, Candida rugosa lipase as an enantioselective catalyst in the esterification of methyl branched carboxylic acids: resolution of rac-3,7-dimethyl-6-octenoic acid (citronellic acid) Tetrahedron-asymmetry. ,vol. 10, pp. 1821- 1826 ,(1999) , 10.1016/S0957-4166(99)00178-0
Sandra F. Mayer, Andreas Steinreiber, Marian Goriup, Robert Saf, Kurt Faber, Chemoenzymatic asymmetric total syntheses of a constituent of Jamaican rum and of (+)-Pestalotin using an enantioconvergent enzyme-triggered cascade reaction Tetrahedron: Asymmetry. ,vol. 13, pp. 523- 528 ,(2002) , 10.1016/S0957-4166(02)00124-6
Anna de Raadt, Barbara Fetz, Herfried Griengl, Markus Florian Klingler, Irene Kopper, Birgit Krenn, Dieter Franz Münzer, René Georg Ott, Peter Plachota, Hans Jörg Weber, Gerhard Braunegg, Winfried Mosler, Robert Saf, Chiral Auxiliaries as Docking/Protecting Groups in Biohydroxylation: The Hydroxylation of Enantiopure Spirooxazolidines Derived from Cyclopentanone Using Beauveria bassiana ATCC 7159 European Journal of Organic Chemistry. ,vol. 2000, pp. 3835- 3847 ,(2000) , 10.1002/1099-0690(200012)2000:23<3835::AID-EJOC3835>3.0.CO;2-E
Richard C Lloyd, Michael C Lloyd, Mark E.B Smith, Karen E Holt, Jonathan P Swift, Philip A Keene, Stephen J.C Taylor, Raymond McCague, Use of hydrolases for the synthesis of cyclic amino acids Tetrahedron. ,vol. 60, pp. 717- 728 ,(2004) , 10.1016/J.TET.2003.10.116
Kenneth Williams, Edmund Lee, Importance of Drug Enantiomers in Clinical Pharmacology Drugs. ,vol. 30, pp. 333- 354 ,(1985) , 10.2165/00003495-198530040-00003