Mechanical and morphological effects of strain rate on fatigue of compact bone.

摘要: Compact bone specimens were cyclically loaded in uniaxial tension for one million cycles; loading was performed at either of two physiological strain rates (0.01 s−1 or 0.03 s−1) and a range (0–1200 microstrain). Microdamage nonloaded control then assessed histomorphometrically. Fatigue, evidence by stiffness loss, observed both significantly greater the high experimental rate than low rate. Morphologically, this fatigue corresponded to increased numbers microcracks bone. These data show that resultant microdamage are realistic expectations cyclic within range. The which strains developed influences behavior compact bone, suggesting rates, characteristic vigorous activities, is more damaging lower rates.