Maternal DRD2, SLC6A3, and OXTR genotypes as potential moderators of the relation between maternal history of care and maternal cortisol secretion in the context of mother-infant separation.
作者： Jaclyn A. Ludmer , Brittany Jamieson , Andrea Gonzalez , Robert Levitan , James Kennedy
DOI: 10.1016/J.BIOPSYCHO.2017.09.004
关键词:
摘要: A mother's cortisol secretion is importantly associated with her own mental health and infant's secretion. This study investigated the influences of maternal history care DRD2, SLC6A3, OXTR genotypes on in context infant stress. community sample 296 mother-infant dyads completed a separation at age 17 months. Maternal salivary cortisol, buccal cells, self-reported were collected. Multilevel models revealed that had greater influence baseline (but not trajectory) for mothers more plasticity alleles SLC6A3 (10R) (G), relative to fewer or no alleles. Findings indicate related anticipation stress, but this relation depends genetic characteristics. are discussed protective system anticipatory
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