Adjuvant Chemotherapy in Older Adults With Colon Cancer

摘要: Colorectal cancer (CRC) is predominately a disease of older adults, with the median age diagnosis 68 years; 59% all cases are diagnosed in persons 65 years or older. Although patients have been underrepresented clinical trials, pooled analysis suggests similar treatment benefits fluorouracil and leucovorin (5FU/LV) for compared younger patients, while evidence benefit from oxaliplatin-containing regimens less compelling. Many helpful tools that provide estimates prognosis, risk recurrence, severe toxicity chemotherapy, functional can aid decisions. In this review, we present adjuvant chemotherapy discuss decision making, suggested approach to adults CRC.