Implications of secondary findings for clinical contexts

摘要: Abstract Deciding how best to deal with unsought diagnostic or prognostic information provided by NGS techniques is one of the key issues for viable translation genomics into clinical practice. The ACMG list secondary findings strategy resolving issue “additional” genomic in adult care, but it not only model. Examples and translational from United States, Kingdom, Australia, Germany, France, Japan, Singapore, Estonia, Canadian province Quebec illustrate a range approaches additional findings. Other cases, including testing pediatric prenatal populations, lifestyle wellness applications, neonatal screening different contexts which must be considered. In each case, practical, organizational, economic, legal, ethical aspects dealing taken account when deciding proceed.