Iron, Oxygen Radicals, and Disease

作者: Sally K. Nelson , Joe M. McCord

DOI: 10.1016/S1569-2558(08)60036-3

关键词:

摘要: Publisher Summary In controlled moderation, both free radical formation and the ingestion of iron are biological necessities. excess, may contribute to serious damage. Iron depletion due regular phlebotomy indeed protect male population from various diseases associated with this trace element. The chapter carefully considers whether an entire should be supplemented treat a few, who would actually benefit such fortification. It was once believed that if good for people then more it even better. is time take step back re-evaluate fortification policies, especially in light mounting evidence against excess role plays so many diseases.

参考文章(183)
K. S. Johansen, S. Hollán, Adequate iron stores and the 'Nil nocere' principle. Haematologia. ,vol. 25, pp. 69- 84 ,(1993)
M J O'Connell, H Baum, T J Peters, Haemosiderin-like properties of free-radical-modified ferritin. Biochemical Journal. ,vol. 240, pp. 297- 300 ,(1986) , 10.1042/BJ2400297
Stanley H. Appel, P. Perkins, J. F. Annegers, J. Lee, Amyotrophic lateral sclerosis mortality rates in Harris County, Texas. Advances in Neurology. ,vol. 56, pp. 239- 243 ,(1991)
David A. Sears, Anemia of chronic disease. Medical Clinics of North America. ,vol. 76, pp. 567- 579 ,(1992) , 10.1016/S0025-7125(16)30340-6
Jack Rogers, Linda Lacroix, Gerald Durmowitz, Kristen Kasschau, James Andriotakis, Kenneth R. Bridges, The Role of Cytokines in the Regulation of Ferritin Expression Advances in Experimental Medicine and Biology. ,vol. 356, pp. 127- 132 ,(1994) , 10.1007/978-1-4615-2554-7_14
R. Bolli, B. S. Patel, W. X. Zhu, P. G. O'Neill, C. J. Hartley, M. L. Charlat, R. Roberts, The iron chelator desferrioxamine attenuates postischemic ventricular dysfunction American Journal of Physiology-heart and Circulatory Physiology. ,vol. 253, ,(1987) , 10.1152/AJPHEART.1987.253.6.H1372
L R Harris, M H Cake, D J Macey, Iron release from ferritin and its sensitivity to superoxide ions differs among vertebrates Biochemical Journal. ,vol. 301, pp. 385- 389 ,(1994) , 10.1042/BJ3010385
Lee Gr, The anemia of chronic disease. Seminars in Hematology. ,vol. 20, pp. 61- 80 ,(1983)
R. S. Sohal, U. T. Brunk, Lipofuscin as an indicator of oxidative stress and aging. Advances in Experimental Medicine and Biology. ,vol. 266, pp. 17- 29 ,(1989) , 10.1007/978-1-4899-5339-1_2
K. N Prasad, Vitamins, nutrition and cancer Karger. ,(1984)