The synthesis and role of taurine in the Japanese eel testis

摘要: In teleost fish, the progestin 17α, 20β-dihydroxy-4-pregnen-3-one (DHP) is an essential component of spermatogenesis pathway. a series investigations on mechanisms underlying progestin-stimulated spermatogenesis, we have found that DHP up-regulates expression cysteine dioxygenase1 (CDO1) in Japanese eel testis. CDO1 one enzymes involved taurine biosynthesis To evaluate whether synthesized testis, sulfinate decarboxylase (CSD), another enzyme synthesis, was isolated from this species. RT-PCR and vitro testicular culture revealed although CSD also expressed neither nor other sex steroids affect mRNA similar manner to CDO1. Using system, further investigated effects synthesis HPLC analysis showed treatment significantly increases levels These results suggest promotes via up-regulation during spermatogenesis. Furthermore, observed our does not induce complete it spermatogonial DNA Spo11, meiosis-specific marker. data thus augments promotion proliferation and/or meiosis hence plays important roles