New Approaches Towards Monoamino Polyglycerol Dendrons and Dendritic Triblock Amphiphiles
作者： Monika Wyszogrodzka , Katrin Möws , Stefan Kamlage , Joanna Wodzińska , Bernd Plietker
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摘要: In order to improve the water solubility of nonpolar compounds such as drugs or dyes, new amphiphilic molecules are needed. this paper we describe a class triblock amphiphiles that have synthesized by straightforward convergent approach. These each consist biphenyl core and polar shell based on various generations monoamino polyglycerol dendrons, coupled through amide linkages (1). For synthesis these dendrons applied simple iterative two-step process allylation an alcohol group catalytic dihydroxylation. As starting materials, D,L-serine/serinol – in second, similar pathway commercially available triglycerol were used. The transport behavior defined was then investigated with dye Nile Red water.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
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